Smile Foundation establishes partnerships and builds networks with national and international development institutions with the prime objective to connect to their domain expertise, resources, and strengths, with its own developmental initiatives undertaken at the grassroots level.
Along with the expansion and strengthening of existing programmes, Alliances at Smile, focuses also on bringing innovations in its programmes through this association with the developmental actors of the world.

Many prominent development agencies, donor organizations, academic institutions, confederations and associations across the globe have joined hands with Smile to further its development initiatives.